名称: メトキシポリ(エチレングリコール)アミン
製品略称: mPEG-NH2
分子量: 2K、5K、10K、20K、40K
包装サイズ: 1g、5g、10g、100g、1kg、10kg
保存温度: -20±5℃
物理的形状: 粒状固体
色: 白からオフホワイト
Structure and Properties Structure: mPEG-NH2 comprises two components, mPEG (methoxypolyethylene glycol) and NH2 (amine). The mPEG segment is a linear or branched polymer composed of repeating ethylene glycol units, terminated with a methoxy group, providing mPEG-NH2 with good water solubility and biocompatibility. The NH2 segment is an amino group, imparting reactivity and functionality to mPEG-NH2. Properties: Water Solubility: mPEG-NH2 exhibits excellent water solubility, dispersing well in water to form transparent solutions. Biocompatibility: Due to its biocompatibility, mPEG-NH2 finds broad applications in the field of biomedicine. Reactivity: The amino functional group in mPEG-NH2 can undergo covalent bonding with other functional groups (such as carboxylic acids, aldehydes, ketones, etc.), enabling specific biological modifications or functionalizations.
Applications Drug Modification: mPEG-NH2 is commonly used to modify protein drugs by forming covalent bonds, thereby reducing immunogenicity and improving stability. Biomedical Material Preparation: mPEG-NH2 is also utilized in the preparation of hydrogels, microspheres, and other biomedical materials, involving polymerization, cross-linking, and other chemical reactions. Drug Delivery: In drug delivery systems, mPEG-NH2 serves as a carrier or modifier to enhance drug targeting and bioavailability. Gene Therapy: In gene therapy, mPEG-NH2 is used to modify gene vectors, enhancing their stability and transfection efficiency.
Storage Conditions mPEG-NH2 should be stored refrigerated, avoiding repeated freeze-thaw cycles to maintain its stability and activity.
Precautions Despite the promising applications of mPEG-NH2 in biomedicine, it is intended for research purposes only and should not be used directly in humans.
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Name | Abbreviation | CAS# |
---|---|---|
Methoxypoly(ethylene glycol) amine | mPEG-NH2 | 80506-64-5 |
Methoxypoly(ethylene glycol) propylamine | mPEG-CH2CH2CH2-NH2 | |
Methoxypoly(ethylene glycol) carboxymethyl | mPEG-CM | |
Methoxypoly(ethylene glycol) propionic acid | mPEG-PA | |
Methoxypoly(ethylene glycol) butanoic acid | mPEG-BA | |
Methoxypoly(ethylene glycol) succinate acid | mPEG-SA | |
Methoxypoly(ethylene glycol) succinimidyl acid | mPEG-SAA | |
Methoxypoly(ethylene glycol) valerianic acid | mPEG-VA | |
Methoxypoly(ethylene glycol) glutamidyl acid | mPEG-GAA | |
Methoxypoly(ethylene glycol) glutarate acid | mPEG-GA | |
Methoxypoly(ethylene glycol) hexanoic acid | mPEG-HA | |
Methoxypoly(ethylene glycol) thiol | mPEG-SH | |
Methoxypoly(ethylene glycol) propionaldehyde | mPEG-pALD | 125061-88-3 |
Methoxypoly(ethylene glycol) maleimide(ether) | mPEG-MAL | 99126-64-4 |
Methoxypoly(ethylene glycol) succinimidyl carbonate | mPEG-SC | 92451-01-9 |
Methoxypoly(ethylene glycol) nitrophenyl carbonate | mPEG-NPC | |
Methoxypoly(ethylene glycol) succinimidyl carboxymethyl ester | mPEG-SCM | |
Methoxypoly(ethylene glycol) succinimidyl propionate | mPEG-SPA | 622405-78-1 |
Methoxypoly(ethylene glycol) succinimidyl succinate | mPEG-SS | |
Methoxypoly(ethylene glycol) succinimidyl glutarate | mPEG-SG | |
Methoxypoly(ethylene glycol) azide | mPEG-N3 | 89485-61-0 |
メトキシポリ(エチレングリコール)アクリレート | mPEG-AA | 32171-39-4 |
メトキシポリ(エチレングリコール)メタクリレート | mPEG-MA | 26915-72-0 |
メトキシポリ(エチレングリコール)ビニルスルホン | mPEG-VS | |
メトキシポリ(エチレングリコール)アミン塩酸塩 | mPEG-NH2·HCl |